Janumet is a prescription medication containing sitagliptin (50mg) and metformin hydrochloride (1000mg) used to treat type 2 diabetes. Each pack contains 58 film-coated tablets. This combination medication helps control blood sugar levels by working in multiple ways to improve insulin production and reduce glucose production. Janumet should be taken twice daily with meals to help reduce stomach side effects. The tablets should not be split, crushed or broken. This medication requires a prescription and regular monitoring by a healthcare provider. Common side effects may include stomach upset, diarrhea, and upper respiratory tract infection. Not recommended for patients with type 1 diabetes or diabetic ketoacidosis. Store at room temperature away from moisture and heat.