La Roche-Posay Redermic R is an intensive anti-aging treatment featuring pure retinol to visibly reduce wrinkles and fine lines while improving skin texture. This dermatologically-tested formula is suitable for sensitive skin and provides gradual retinol release for optimal effectiveness and tolerance. Redermic R contains a combination of pure retinol and gradual-release retinol to help minimize the appearance of aging signs while being gentle enough for sensitive skin. For best results, apply in the evening to clean, dry skin. Start with using it 2-3 times per week and gradually increase frequency as tolerated. Always use sunscreen during the day when using retinol products. Not recommended during pregnancy or breastfeeding.