La Roche Posay Retinol B3 Serum is an anti-aging face and neck treatment that combines pure retinol with vitamin B3 to help reduce the appearance of wrinkles and fine lines while being gentle enough for sensitive skin. The serum provides hydration and skin renewal benefits with a lightweight texture. The serum should be applied in the evening, using 3-4 drops on cleansed face and neck before moisturizer. Sunscreen application is essential the following day. The pure retinol may turn yellow when exposed to air, but this does not affect its efficacy or tolerance. The formula is designed for gradual release to ensure optimal effectiveness while maintaining skin comfort.