Probiotics are well documented to help support the good bacteria in your GI tract responsible for digestion, immunity and overall wellness. Taken together, cranberry with probiotics may help to encourage both better urinary tract and digestive health. D-mannose might help treat a deficiency caused by a genetic defect. D-mannose might also prevent certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection. D-mannose is used for an inherited disorder called carbohydrate-deficient glycoprotein syndrome type 1b.