Mefenamic acid is a non-steroidal anti-inflammatory agent with analgesic properties, and a demonstratable antipyretic effect. It has been shown to inhibit prostaglandin activity. Indications 1. As an anti-inflammatory analgesic for the symptomatic relief of rheumatoid arthritis (including Still's Disease), osteoarthritis, and pain including muscular, traumatic and dental pain, headaches of most aetiology, post-operative and post-partum pain, pyrexia in children. 2. Primary dysmenorrhoea in older children. Posology Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms (see section 4.4). Do not exceed the stated dose. Paediatric population It is recommended that children under 12 years of age should be given Mefenamic Acid Suspension (50mg/5ml) in the following dosage regime: Infants over 6 months-– 25mg/kg of bodyweight daily in divided doses 6 months to under 2 years– one 5 ml spoonful 2 years to under 5 years– two 5 ml spoonfuls 5 years to under 9 years– three 5 ml spoonfuls 9 years to 12 years– four 5 ml spoonfuls Doses may be repeated as necessary, up to three times daily. Mefenamic acid suspension should be taken preferably with or after food. Apart from the treatment of Still's Disease, therapy should not be continued for longer than 7 days in children. Although mefenamic acid suspension is not indicated to be used by the elderly, if used in elderly patients, these patients are at increased risk of the serious consequences of adverse reactions. If an NSAID is considered necessary, the lowest effective dose should be used and for the shortest possible duration. The patient should be monitored regularly for GI bleeding during NSAID therapy. Method of administration For oral administration.