Zofran Melt 8mg is a prescription medication containing ondansetron in an oral dissolving tablet form. Each pack contains 10 melt units that dissolve quickly in the mouth. This formulation is designed for easy administration of the anti-nausea medication. The active ingredient ondansetron belongs to a class of medications called serotonin 5-HT3 receptor antagonists. The melt formulation contains additional ingredients including gelatin, strawberry flavor, mannitol, and sodium propylhydroxybenzoate to create a tablet that dissolves rapidly when placed on the tongue. This format can be beneficial for patients who have difficulty swallowing traditional tablets.